single elective embryo transfer baby

Elective Single Embryo Transfer in
San Diego


What is eSET?

Elective single embryo transfer (eSET) is defined as the transfer of a single embryo, whether it is at the cleavage stage (2-3 days after fertilization) or at the blastocyst stage (5-6 days after fertilization). The primary rationale for performing eSET is to reduce the multiple pregnancy rate associated with IVF. Approximately 30% of IVF pregnancies result in a twin pregnancy and another 3-4% result in a triplet or a higher order (four or more implanted embryos) pregnancy in the United States.

Multiple pregnancies can significantly increase the risks and complications to both mother and babies. In general, mothers have a higher risk for hypertension, gestational diabetes, preeclampsia, eclampsia, premature labor and delivery. Premature delivery can lead to long-term lung and gastrointestinal problems, cerebral palsy and even neonatal death.

When eSET is used in conjunction with PGT-A, it provides for unparalleled success rates for delivering one healthy child.

SDFC IVF graduate

Who Would Benefit from a single embryo transfer?

In general, pregnancy rates are highest when the highest quality embryo is transferred. The embryo quality is a function of the woman age and ovarian reserve.

Some of the patients who would benefit from eSET include:

  • Women younger than 38 years of age with normal ovarian reserve testing.
  • First IVF cycle.
  • Presence of a large number of high-quality embryos.
  • Availability of embryos for cryopreservation.
  • When used in conjunction with PGT-A to transfer 1 genetically normal (euploid) embryo.

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