Elective single embryo transfer (eSET) is defined as the transfer of a single embryo, whether it is at the cleavage stage (2-3 days after fertilization) or at the blastocyst stage (5-6 days after fertilization). The primary rationale for performing eSET is to reduce the multiple pregnancy rate associated with IVF. Approximately 30% of IVF pregnancies result in a twin pregnancy and another 3-4% result in a triplet or a higher order (four or more implanted embryos) pregnancy in the United States.
Multiple pregnancies can significantly increase the risks and complications to both mother and babies. In general, mothers have a higher risk for hypertension, gestational diabetes, preeclampsia, eclampsia, premature labor and delivery. Premature delivery can lead to long-term lung and gastrointestinal problems, cerebral palsy and even neonatal death.
When eSET is used in conjunction with PGT-A, it provides for unparalleled success rates for delivering one healthy child.
In general, pregnancy rates are highest when the highest quality embryo is transferred. The embryo quality is a function of the woman age and ovarian reserve.
Some of the patients who would benefit from eSET include:
We welcome the opportunity to answer any questions you may have about your fertility treatment. Here at Fertility Institute of San Diego, you will be treated with compassion and care.